Palmitoylethanolamide (P.E.A) Capsules for Dogs & Cats
Palmitoylethanolamide (P.E.A) is a naturally occurring fatty acid amide that supports the body’s endocannabinoid system — helping regulate inflammation, calm pain signals, and stabilise mast cells involved in allergic reactions.
Supplementing with ultra-micronised P.E.A provides gentle, non-sedating support for dogs experiencing discomfort, inflammation, or allergic skin conditions.
How P.E.A Supports Your Pet
P.E.A works by helping regulate the body’s inflammatory response and modulating pain signalling pathways. It indirectly activates cannabinoid receptors (CB1 and CB2) as well as PPAR-alpha and other receptors involved in inflammation control.
Research has shown P.E.A may support dogs experiencing:
✔ Joint pain, arthritis, and nerve discomfort
✔ Chronic itching, redness, and inflammatory skin conditions
✔ Allergies and atopic dermatitis
✔ Digestive inflammation including IBD
✔ Post-surgical discomfort
✔ Age-related cognitive decline
Why Choose P.E.A?
P.E.A has been studied since 1957 and is recognised as a natural anti-inflammatory and analgesic compound.
Clinical research involving more than 5,000 patients and 500+ scientific publications has documented its safety and efficacy.
Benefits include:
✔ Gentle, non-sedating support suitable for long-term use
✔ Naturally produced in the body and found in some foods
✔ Supports pain, inflammation and immune balance
✔ Safe to use alongside veterinary medications
✔ Can be combined with omega-3s or gut support for comprehensive wellness
Ingredients
Ultra-micronised Palmitoylethanolamide (P.E.A) in a cellulose capsule.
Directions & Dosage
Give twice daily (morning and evening) approximately 12 hours apart, or as recommended by your animal healthcare professional.
Can be given with or without food.
Dosage guidelines:
-
1–20 kg → 300 mg
-
20–30 kg → 600 mg
-
30–65 kg → 1000 mg
Please refer to the bottle for exact dosing instructions.
Storage
Store below 25°C in a cool, dry place out of direct sunlight.
Keep container tightly closed.
The Science
Abramo, F., Campora, L., Albanese, F., della Valle, M. F., Cristino, L., Petrosino, S., ... & Miragliotta, V. (2014). Increased levels of palmitoylethanolamide and other bioactive lipid mediators and enhanced local mast cell proliferation in canine atopic dermatitis. BMC Veterinary Research, 10, 1-10.
Cerrato, S., Brazis, P., Della Valle, M. F., Miolo, A., Petrosino, S., Di Marzo, V., & Puigdemont, A. (2012). Effects of palmitoylethanolamide on the cutaneous allergic inflammatory response in Ascaris hypersensitive Beagle dogs. The Veterinary Journal, 191(3), 377-382.
della Rocca, G.; Re, G. Palmitoylethanolamide and Related ALIAmides for Small Animal Health: State of the Art. Biomolecules 2022, 12, 1186. https://doi.org/10.3390/biom12091186
della Rocca G, Gamba D. Chronic Pain in Dogs and Cats: Is There Place for Dietary Intervention with Micro-Palmitoylethanolamide? Animals. 2021; 11(4):952. https://doi.org/10.3390/ani11040952
Gugliandolo E, Peritore AF, Piras C, Cuzzocrea S, Crupi R. Palmitoylethanolamide and Related ALIAmides: Prohomeostatic Lipid Compounds for Animal Health and Wellbeing. Veterinary Sciences. 2020; 7(2):78. https://doi.org/10.3390/vetsci7020078
Noli, C., Della Valle, M. F., Miolo, A., Medori, C., Schievano, C., & Skinalia Clinical Research Group. (2015). Efficacy of ultra‐micronized palmitoylethanolamide in canine atopic dermatitis: an open‐label multi‐centre study. Veterinary dermatology, 26(6), 432-e101.
Petrosino, S., Schiano Moriello, A., Cerrato, S., Fusco, M., Puigdemont, A., De Petrocellis, L., & Di Marzo, V. (2016). The anti‐inflammatory mediator palmitoylethanolamide enhances the levels of 2‐arachidonoyl‐glycerol and potentiates its actions at TRPV1 cation channels. British Journal of Pharmacology, 173(7), 1154-1162.
Re, G., Barbero, R., Miolo, A., & Di Marzo, V. (2007). Palmitoylethanolamide, endocannabinoids and related cannabimimetic compounds in protection against tissue inflammation and pain: potential use in companion animals. The Veterinary Journal, 173(1), 21-30.
Scuderi C, Golini L. Successful and Unsuccessful Brain Aging in Pets: Pathophysiological Mechanisms behind Clinical Signs and Potential Benefits from Palmitoylethanolamide Nutritional Intervention. Animals. 2021; 11(9):2584. https://doi.org/10.3390/ani11092584
Why we the sell the items we sell
Our aim is simple, to extend and improve quality of life of dogs & cats. We aim to do this by sourcing natural healthy alternatives to many of the toxic and chemically laden products on the market for our beloved pets and by sharing our knowledge and experience of nutrition, natural remedies and cleansing your pet of toxins.
We are passionate about natural nutrition and see it as the fundamental essential for good health. A varied fresh whole food diet with minimal processed foods and minimising chemical and toxin exposure is essential to your pets health and wellbeing.
We are also passionate about reducing stress, physical & psychological pain in our dogs lives through equipment, training and activity choices.
WE ARE COMMITTED TO WORKING
TOWARD A WASTE-FREE FUTURE
Our AP branded treat bags are 100% recyclable plastic
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